Developmental Outcomes of Children Born After Assisted Reproductive Technologies

Developmental Outcomes of Children Born After Assisted Reproductive Technologies

Since the birth of Louise Brown in England more than 25 years ago, an estimated 2 million children have been born worldwide through in vitro fertilization and related assisted reproduction technology (ART) procedures. Most children born after ART are healthy and develop without complications. Largely because of multiple births (twins, triplets, etc), however, some ART offspring experience devel...

Endometriosis and assisted reproductive technologies: maximizing outcomes.

In vitro fertilization (IVF) represents the most efficient means of overcoming endometriosis-related infertility. Compromised pelvic anatomy and a hostile peritoneal environment are bypassed. Despite the results of early trials, more contemporary outcomes data would suggest that when controlled for age, IVF cycle outcome is not compromised by the presence of endometriosis. One exception to this...

A Review of Outcome Data concerning Children Born following Assisted Reproductive Technologies

Assisted reproductive technologies (ARTS) are used for more than 30 years to help infertile couples. Concerns about long-term health of children conceived following ART have led to start follow-up studies. Despite methodological limitations and discrepant results, many of the studies and meta-analyses have reported an increased risk of birth defects after ART. Etiologies may be multiple births,...

Imprinting disorders after assisted reproductive technologies.

PURPOSE OF REVIEW To assess the evidence of an increased risk of imprinting diseases in children born after use of assisted reproductive technologies. RECENT FINDINGS Imprinting disorders occur when the epigenetic programming during gametogenesis is disturbed, or when this programming is not sufficiently sustained during the process of fertilization and early embryonic development. Ten case o...

Reaffirming human dignity in disputes over children born from assisted reproductive technologies.